I've never had a problem with nicotine from any cigar. I don't know if one has ever even given me a buzz. But there is a couple pipe tobaccos that can get me a little light headed. Man tobacco I call them When that happens, I find that Sweet Tea or Coke gets rid of the spins real fast. I haven't been nauseous from tobacco since I was in middle school, so no advice there

Another thing to consider is only smoking smaller vitola's until you become more accustomed to the vitamin N hit.

As far as palate fatigue is concerned though, it is definitely a real thing. I find that if I smoke a lot of full bodied things back to back to back that all the flavors start to become muddled. Or if I smoke something heavy, then something mild after it. Water really helps clear things up too. Not beer or bourbon...which is what I usually am drinking when smoking...